.bd-placeholder-img {
  font-size: 1.125rem;
  text-anchor: middle;
  -webkit-user-select: none;
  -moz-user-select: none;
  -ms-user-select: none;
  user-select: none;
}

.btn-group-lg>.btn,
.btn-lg,
.btn-outline-success,
.btn-outline-primary,
.btn-primary,
.btn-secondary {
  border-radius: 4.5rem;
}

.btn-outline-primary {
  border-color: #0067ce;
  color: #0067ce;
}

.btn-outline-primary:hover {
  background-color: #0067ce;
}

.btn-primary {
  background-color: #0067ce;
}

.btn-primary:hover {
  background-color: #007bff;
}

body {
  font: 1rem "PT Sans", Arial, sans-serif;
  line-height: 1;
  color: #404040;
  /*background: url("/images/phoned.png") 0 0 no-repeat;*/
  background: url("/images/back_roshe_3.png") 0 0 repeat;
  /*background-attachment: fixed;*/
}

a {
  color: #0067ce;
}

a:hover {
  color: #007bff;
}

.border-bottom {
  border-bottom: 1px solid #0067ce !important;
}

.container {}

header {
  position: fixed!important;
  top: 0!important;
  left: 0;
  width: 100%;
  z-index: 1010;
  transition: box-shadow 0.5s ease-out;
  background: #f4f4f4;
}

.header.scroll {
  border-bottom: 2px solid #f4f4f4;
  box-shadow: 0px 0px 20px rgba(0, 0, 0, 0.1);
}

.content {
  padding-top: 7rem;

  /*background: url("/images/phoned_bg.png") bottom right no-repeat;*/
}

.content .container {
  background: #fff;
  border-radius: 10px;
  padding-top: 15px;
}

.content .col-md-8 {
  background: #fff;
}

.content h1,
h2,
h3 {
  font-family: "PT Sans Caption", "PT Sans", Arial, sans-serif;
  font-weight: bold;
}

.content h2 {
  font-size: 1.8rem;
}

.menu-cont a.nav-link {
  font: 1rem "PT Sans", Arial, sans-serif;
  line-height: 1;
  color: #404040;
  text-decoration: none;
  padding-top: 1.5rem;
  padding-bottom: 1.5rem;
  border-bottom: 2px solid #f4f4f4;
  -webkit-transition: border 500ms ease-out;
  -moz-transition: border 500ms ease-out;
  -o-transition: border 500ms ease-out;
  transition: border 500ms ease-out;
  font-weight: bold;
}

.menu-cont .navbar {
  padding: 0rem 1rem;
}

.menu-cont a.nav-link:hover {
  color: #0067ce;
  border-bottom: 2px solid #0067ce;
}

.navbar-toggler {
  background: #0067ce;
  border-radius: 50%;
  line-height: 31px;
}

.navbar-toggler span {
  color: #fff;
}

.registr-btn {
  margin-right: 10px;
}

footer {
  background: #f4f4f4;
  font-size: 0.9rem;
}

.item img {
  width: 100%;
  border-radius: 10px;
  box-shadow: 0px 0px 20px rgba(0, 0, 0, 0.1);
  border-top: 3px solid #0067ce;
}

.item-title {
  font-weight: 500;
  font-size: 1.4em;
  line-height: 1.2;
  letter-spacing: -0.5px;
  color: #192b37;
}

.item-title:hover {
  color: #0067ce;
  text-decoration: none;
}

.item-desc {
  font-weight: 500;
  font-size: 1em;
  font-family: "Open Sans", sans-serif;
  color: #192b37;
  line-height: 1.4em;
  margin: 10px 0;
}

.item-date {
  color: #ccc;
  font-size: 12px;
  margin-bottom: 5px;
}

.title-cont {
  background-size: 22px;
  padding: 13px;
}

.type1 {
  background: url("/images/label_6.png") 0 0 no-repeat;
  background-size: 22px;
}

.type2 {
  background: url("/images/label_2.png") 0 0 no-repeat;
  background-size: 22px;
}

.type3 {
  background: url("/images/label_3.png") 0 0 no-repeat;
  background-size: 22px;
}

.type4 {
  background: url("/images/label_1.png") 0 0 no-repeat;
  background-size: 22px;
}

.type5 {
  background: url("/images/label_4.png") 0 0 no-repeat;
  background-size: 22px;
}

.type6 {
  background: url("/images/label_5.png") 0 0 no-repeat;
  background-size: 22px;
}

.video-desc {
  background: url("/images/phoned_2.png") bottom right no-repeat;
  padding-bottom: 50px;
}

.video-item {
  display: block;
  position: relative;
}

.video-item img {
  width: 100%;
  border-radius: 10px;
}

.video-item .overflow-bg {
  position: absolute;
  width: 100%;
  height: 100%;
  background: rgba(254, 254, 254, 0.45);
  z-index: 1;
}

.video-item span.fa-play-circle-o {
  font-size: 64px;
  margin: -32px 0 0 -32px;
  color: #0067ce;
}

.video-item span {
  position: absolute;
  z-index: 2;
  left: 50%;
  top: 50%;
}

.video-item:hover span,
.video-item:hover .overflow-bg {
  display: none;
}

.backgr-grey {
  background: #f4f4f4;
  border-radius: 10px;
}

.block-item {
  border-radius: 10px;
  box-shadow: 0px 0px 20px rgba(0, 0, 0, 0.1);
  padding: 2rem 3rem;
  border-top: 8px solid #0067ce;
  font-weight: 500;
  font-size: 1.1em;
  font-family: "Open Sans", sans-serif;
  color: #192b37;
  line-height: 1.4em;
  margin: 10px 0;
}

h2.title-small {
  font-size: 1.6rem;
}

.anons-conf {
  text-align: center;
}

.anons-conf span {
  font-size: 64px;
  color: #0067ce;
}

.anons-date {
  text-align: left;
  font-style: italic;
  font-size: 1rem;
}

.actual {
  border: 2px solid #eeeeee;
  border-radius: 10px;
}

.links ul {
  list-style: none;
  margin: 0;
  padding: 0;
}

.links ul li {
  margin-bottom: 1rem;
}

.links ul li a {
  color: #000;
  line-height: 1.4rem;
  font-size: 1rem;
}

.links ul li a span {
  color: #0067ce;
}

.img-big img {
  width: 100%;
}

.art-desc {
  text-align: left;
  font-style: italic;
  font-size: 1.4rem;
  line-height: 1.6rem;
}

.art-content {
  font-size: 1rem;
  line-height: 1.4rem;
}

.art-header {
  background: #f4f4f4;
  padding: 20px;
  border-radius: 10px;
  margin-bottom: 30px;
}

.art-header ul {
  list-style: none;
  margin: 0;
  padding: 0 0 0 20px;
}

.art-header ol {
  margin: 0;
  padding: 0 0 0 40px;
}

.art-header ul li,
.art-header ol li {
  margin-bottom: 0.5rem;
}

.art-header ul li a,
.art-header ol li a {
  line-height: 1rem;
  font-size: 0.8rem;
  position: relative;
}

.art-header ul li a:hover,
.art-header ol li a:hover {
  text-decoration: none;
  color: #000;
}

.art-header div {
  padding: 0 0 0 30px;
  background: url("/images/label_4.png") 0 0 no-repeat;
  background-size: 22px;
  font-size: 1.4rem;
  line-height: 1.6rem;
  margin-bottom: 15px;
}

.art-header2 {
  border: 2px solid #eeeeee;
  background: #fff;
}

.art-header2 div {
  background: url("/images/label_2.png") 0 0 no-repeat;
  background-size: 22px;
}

.art-header ul li a:before {
  content: "\f0a4";
  display: inline-block;
  position: absolute;
  left: -26px;
  top: 50%;
  margin-top: -6px;
  font: normal normal normal 14px/1 FontAwesome;
  text-rendering: auto;
  -webkit-font-smoothing: antialiased;
  margin-left: 6px;
  -moz-osx-font-smoothing: grayscale;
  font-size: 12px;
}

.art-header ol li a:before {
  content: "\f0a4";
  display: inline-block;
  position: absolute;
  left: -46px;
  top: 50%;
  margin-top: -6px;
  font: normal normal normal 14px/1 FontAwesome;
  text-rendering: auto;
  -webkit-font-smoothing: antialiased;
  margin-left: 6px;
  -moz-osx-font-smoothing: grayscale;
  font-size: 12px;
}

.protocol {
  border: solid 1px #b7b7b7;
  border-radius: 5px;
  background: #fff;
}

.protocol-title {
  width: 100%;
  display: block;
}

.protocol-link {
  border-left: 1px solid #b7b7b7;
  margin-bottom: 21px;
  font-size: 1rem;
  line-height: 1.2rem;

  padding-left: 17px;
}

.cat-list {
  background: #fff;
  border-radius: 10px;
  box-shadow: 0px 0px 20px rgba(0, 0, 0, 0.1);
  border: 1px solid #0067ce;
  padding-top: 20px;
  padding-bottom: 20px;
}

.nav-active {
  color: #000;
}

.protocol-zmist {
  list-style: none;
  padding: 0;
  margin: 0;
  background: #f5f5f5;
}

.protocol-zmist li:nth-child(odd) {
  background: #f0f0f0;
}

.protocol-zmist li {
  margin: 5px 0;
  padding: 10px 5px 10px 15px;
}

.protocol-zmist li:nth-child(1) {
  border-radius: 10px;
  box-shadow: 0px 0px 20px rgba(0, 0, 0, 0.1);
  padding: 2rem 3rem;
  border-top: 8px solid #0067ce;
  padding-left: 5px;
  font-size: 18px;
  font-weight: bold;
}

.content p,
.content ul,
.content ol {
  line-height: 1.3;
}

.group_check {
  display: -webkit-box;
  display: -ms-flexbox;
  display: flex;
  -webkit-box-pack: start;
  -ms-flex-pack: start;
  justify-content: flex-start;
  -webkit-box-align: center;
  -ms-flex-align: center;
  align-items: center;
}

.group_check .order_check {
  display: block;
  /* width: 20px;
  height: 20px; */
}

.group_check p {
  margin: 0;
  padding: 0 0 0 10px;
}

.m0 {
  margin: 0;
}

@media screen and (max-width: 1280px) {
  .menu-cont a.nav-link {
    font: 0.9rem "PT Sans", Arial, sans-serif;
  }
}

@media screen and (max-width: 1180px) {
  .menu-cont a.nav-link {
    font: 0.7rem "PT Sans", Arial, sans-serif;
  }
}

@media screen and (max-width: 992px) {
  .item-date {
    padding-top: 1rem;
    padding-bottom: 1rem;
  }
}

/* ss */

.roche_logo {
  width: 60px;
}

.footer_list li {
  padding: 5px 0;
}

.dont-show {
  display: none;
}

.show-modal_univ {
  display: block;
  position: absolute;
  -webkit-box-shadow: 0px 0px 13px 0px rgba(0, 0, 0, 0.75);
  box-shadow: 0px 0px 13px 0px rgba(0, 0, 0, 0.75);
}

.first_disclaimer {
  padding-bottom: 30px;
}

.disclaimer_other {
  font-size: 0.9rem;
}

.blue-div {
  background-color: #0067ce;
  color: #fff;
}

.blue-div .modal-title {
  font-weight: bold;
}

.ml10 {
  margin-left: 10px;
}

@media (min-width: 992px) {
  .show-modal_univ {
    left: 25%;
    top: -175px;
  }
}

@media (max-width: 991px) {
  .show-modal_univ {
    left: 0;
    top: 50px;
  }
}

.lightbox__button_univ {
  width: 28px;
  height: 28px;
}

.lightbox__button {
  position: absolute;
  top: 8px;
  right: 8px;
  display: -webkit-box;
  display: -ms-flexbox;
  display: flex;
  -webkit-box-align: center;
  -ms-flex-align: center;
  align-items: center;
  -webkit-box-pack: center;
  -ms-flex-pack: center;
  justify-content: center;
  width: 48px;
  height: 48px;
  padding: 0;
  margin: 0;
  border: none;
  border-radius: 50%;
  background-color: #ccc;
  fill: #000;
  cursor: pointer;
  -webkit-transition: background-color 200ms ease-in-out;
  -o-transition: background-color 200ms ease-in-out;
  transition: background-color 200ms ease-in-out;
  outline: none;
  background-image: url(/images/icon-close.svg);
  background-position: center;
  background-size: 60%;
  background-repeat: no-repeat;
}

footer {
  position: relative;
}

@media (min-width: 768px) and (max-width: 991px) {
  .show-modal_univ {
    left: 12%;
    top: -40px;
  }
}

.footer_to_mail {
  display: -webkit-box;
  display: -ms-flexbox;
  display: flex;
  -webkit-box-pack: space-evenly;
  -ms-flex-pack: space-evenly;
  justify-content: space-evenly;
  -webkit-box-align: center;
  -ms-flex-align: center;
  align-items: center;
  width: 100%;
}

.footer_to_mail p {
  text-align: left;
  margin: 0;
}

/* ss */
@media screen and (max-width: 992px) {
  .menu-cont a.nav-link {
    font: 1rem "PT Sans", Arial, sans-serif;
  }

  .menu-cont a.nav-link {
    padding-top: 1rem;
    padding-bottom: 1rem;
  }

  .navbar-nav>li>.dropdown-menu {
    background-color: rgb(244, 244, 244);
    padding-left: 10px;
  }
}

.content .blue-big {
  color: #2a28b8;
}

.content .blue-small {
  color: #2927b8;
}

.content .rose-color {
  color: #f25991;
}

.content .red-color {
  color: #e61029;
}

.turquise-color {
  color: #116c7a;
}

.content .turquise-button {
  border-radius: 4px;
  display: inline-block;
  font-size: 14px;
  font-weight: bold;
  line-height: 24px;
  padding: 12px 24px 13px 24px;
  text-align: center;
  text-decoration: none;
  transition: opacity 0.1s ease-in;
  color: #ffffff;
  box-shadow: inset 0 -2px 0 0 rgba(0, 0, 0, 0.2);
  background-color: #218c9c;
}

.content .rose-button {
  border-radius: 4px;
  display: inline-block;
  font-size: 14px;
  font-weight: bold;
  line-height: 24px;
  padding: 12px 24px 13px 24px;
  text-align: center;
  text-decoration: none;
  transition: opacity 0.1s ease-in;
  color: #ffffff;
  box-shadow: inset 0 -2px 0 0 rgba(0, 0, 0, 0.2);
  background-color: #eb1a44;
}

.content .blue-button {
  border-radius: 4px;
  display: inline-block;
  font-size: 14px;
  font-weight: bold;
  line-height: 24px;
  padding: 12px 24px 13px 24px;
  text-align: center;
  text-decoration: none;
  transition: opacity 0.1s ease-in;
  color: #ffffff;
  box-shadow: inset 0 -2px 0 0 rgba(0, 0, 0, 0.2);
  background-color: #1a6deb;
}

.bold {
  font-weight: bold;
}

.verde {
  color: #186991;
}

h1.news-header {
  font-size: 2em;
}

.news-content h3 {
  font-size: 1.5em;
}

.wd100 {
  width: 100%;
}
.mw100{
  max-width: 100%;
}

.mb2rem{
  margin-bottom: 2rem;
}

.content .roche-dark_blue{
  color: #092a5f;
}
.content .h1-to-usual_text{
  font-size: 1rem;
  font-weight: 400;
}

.content .text-center{
  text-align: center;
}
.content .italic-underline{
  font-style: italic; 
  text-decoration: underline;
}

.content .flex-center{
  display: flex;
  align-items: center;
}
.standart-video{
  width: 100%;
}
.iframe-pdf {
  width: 100%;
}

@media(max-width:991px){
  .center-end{
    justify-content: center;
  }
  .mt-1rem-991{
    margin-top: 1rem;
  }
  /* .standart-video{
    width: 100%;
    height: 240px;
  } */
  .iframe-pdf {
    height: 50vh;
  }
}
@media(max-width:380px){
  .standart-video{
    height: 180px;
  }
}
@media(min-width:381px) and (max-width:409px){
  .standart-video{
    height: 190px;
  }
}
@media(min-width:410px) and (max-width:767px){
  .standart-video{
    height: 200px;
  }
}

@media only screen 
and (min-device-width : 768px) 
and (max-device-width : 1024px){ 
  .standart-video{
    height: 213px;
  }
 }



@media(min-width:992px){
  .center-end{
    justify-content: flex-end;
  }
  .standart-video{
    width: 100%;
    height: 394px;
  }
  .iframe-pdf{
    height: 75vh;
  }
}
@media(min-width:1200px){
  .mt-1rem-1200{
    margin-top: 1rem;
  }
}

.standart-video{
  margin-bottom: 1rem;
}

.ndfHFb-c4YZDc-Wrql6b, .ndfHFb-c4YZDc-Wrql6b-SmKAyb{
  display: none!important;
}